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A genome-wide methylation analysis revealed that high IMF levels were highly correlated with the hypermethylation of the promoters of three genes: ATP binding cassette subfamily A member 1 ( ABCA1 ), COL6A1 , and glutathione S-transferase theta 1-like ( GSTT1L )

L-carnitine research protocol in isovaleric acidemia [PMID: 6549017] Laboratory literature summary: L-carnitine research protocol in isovaleric acidemia

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Jung et al., 2018

Dose Range: 250 mcg (0.25 mg) to 2400 mcg (2.4 mg) weekly with stepwise titration every 4 weeks to improve tolerability